Axisanté 5 is a medical practice management software published by CompuGroup Medical. It encompasses patient record management, prescriptions, electronic transmission of care sheets, and communication with digital health services. Access to the software relies on several layers of identification that do not all function in the same way.
Axisanté 5 Authentication: Distinguishing User Account and Professional Identity
The most common confusion during a first login concerns the difference between the software identifier and the professional identity. The Axisanté 5 user account relies on a username/password pair defined during installation or assigned by the practice administrator. This pair opens the local interface of the software.
The professional identity, on the other hand, operates at another level. It is based on the RPPS number and a strong authentication method such as the CPS card or e-CPS via Pro Santé Connect. This layer is required to access the national services integrated into the software (MSSanté, DMP, My health space).
In practice, a practitioner can easily open Axisanté 5 with their local identifier, check their appointments, write an observation, and then be denied access to the DMP because their CPS card is not inserted into the reader or their authorization is not up to date. Two distinct authentications coexist within the same software, and a failure in one does not indicate a problem in the other.
To connect to Axisanté 5 without blocking, the first step is to verify which level of access is causing the problem before attempting to reset anything.
Online Access to Axisanté 5: The Role of Ségur Referencing

The online space of Axisanté 5 is not limited to a simple web version of the software. The connected functions (consultation of the DMP, sending documents via MSSanté, feeding My health space) depend on the Ségur referencing of digital health. This referencing ensures that the software meets the interoperability requirements set by the State.
Without this referencing, a medical software cannot exchange data with national services, even if the practitioner has a valid CPS card. Axisanté 5 is Ségur referenced, allowing it to integrate these flows directly into the consultation interface.
A technical point deserves attention: the Simplified AIR mode. This system allows consultation of documents from My health space directly from the business software, without opening a separate portal or re-authenticating at each access. The prerequisites are as follows:
- The software must be referenced and compatible with the Simplified AIR mode
- The practitioner must have a verified professional identity (valid RPPS, active strong authentication method)
- The access authorizations to the patient’s DMP must be in order, which implies the patient’s consent or a documented care situation
The Simplified AIR mode eliminates double authentication for DMP consultation, provided these prerequisites are met. If access fails despite a functional local connection, the problem almost always lies with the authorization or the strong authentication method.
Pro Santé Connect and e-CPS: Configuring Strong Authentication in Axisanté
Pro Santé Connect is the digital identity provider for healthcare professionals in France. It is gradually replacing the sole physical CPS card with a range of authentication methods, including e-CPS on smartphones.
In Axisanté 5, the configuration of Pro Santé Connect is done through the software settings. The practitioner associates their RPPS identity with the software and then chooses their authentication method. Two scenarios arise:
- CPS card inserted into a physical reader connected to the workstation: authentication is done by reading the card and entering the PIN code
- e-CPS via the mobile application: the software displays a QR code or sends a notification, which the practitioner validates from their phone
The e-CPS offers a practical advantage in mobility or when the card reader malfunctions. The activation of e-CPS is done on the portal of the Digital Health Agency, independently of Axisanté. Once activated, it can be used in all software compatible with Pro Santé Connect.
A common pitfall: the practitioner activates e-CPS but does not update the authentication settings in Axisanté. The software then continues to look for the physical CPS card and denies access to connected services.
Password Management and Account Access Recovery for Axisanté

Loss of the local password for Axisanté 5 is not handled in the same way as the loss of a traditional online service password. Since the software is installed on the practice’s workstation, resetting it generally goes through the system administrator or the technical support of CompuGroup Medical.
Here are some practical tips to avoid blocking:
- Activate password management in the security settings of the software upon installation, allowing for the definition of complexity and renewal rules
- Keep a separate administrator access distinct from practitioner access, to be able to reset a user password without external intervention
- Do not confuse the Axisanté password with the PIN code of the CPS card, which follows a different unlocking procedure (via the professional order or the Digital Health Agency)
A blocked password on the CPS card cannot be reset from Axisanté. This distinction prevents calls to technical support for a problem that does not pertain to the software.
Training offered by referenced organizations covers data security and the proper use of integrated communication tools. They specifically address the configuration of MSSanté and the management of access rights within a practice involving multiple practitioners.
Connecting to Axisanté 5 relies on a two-level architecture that most online guides treat as a single block. Identifying whether the blockage comes from the local identifier, the CPS card, the e-CPS, or a missing DMP authorization allows for resolving the issue in a few minutes instead of going through a complete reset procedure.



